Jose Angel Moreno-Cabezuelo
Postdoctoral Researcher
Biography
I obtained my undergraduate degree in Environmental Sciences at the University of Granada, in Spain. Staying in Granada, I achieved a Masters degree in Agrarian Biology and Aquaculture. Since 2016, I have been working with marine cyanobacteria of great environmental importance, specifically Prochlorococcus and Synechococcus, contributing to the understanding of the adaptive mechanisms that have allowed these two genera to be ecologically successful. After my masters, I did my PhD from 2016-19 in the Department of Biochemistry and Molecular Biology at the University of Córdoba (UCO), in Spain, working in the Cyanotrans team. During my PhD, I determined that mixotrophy confers an evolutionary advantage to Prochlorococcus and Synechococcus, in oligotrophic areas in the oceans, over other microorganisms which share their ecological niche. Through metabolomic and proteomic analysis I demonstrated that Prochlorococcus and Synechococcus take up and use glucose.
My current project, is to develop the fastest growing cyanobacterium identified to date, as a renewable platform for high value terpenes, as well as to carry out large-scale growth and commercialization in collaboration with industrial partners. This work is crucial to establishing a platform for production of chemicals currently derived from petroleum or agricultural based sources and the development of a low carbon economy.
Recent publications
-Muñoz-Marín MC*, Gómez-Baena G*, López-Lozano A, Moreno-Cabezuelo JA, Díez J & García-Fernández JM (2020) Mixotrophy in marine cyanobacteria: use of organic compounds by Prochlorococcus and Synechococcus. The ISME Journal 14, 1065–1073.
doi 10.1038/s41396-020-0603-9.
We posted a “Behind the paper” comment at the Nature Microbiology Research Community.
-Moreno-Cabezuelo JA, López-Lozano A, Díez J & García-Fernández JM (2019) Differential expression of the glucose transporter gene glcH in response to glucose and light in marine picocyanobacteria. PeerJ 6:e6248. doi 10.7717/peerj.6248.
-Moreno-Cabezuelo JA, Gómez-Baena G, Díez J & García-Fernández JM. Integrated proteomic and metabolomic analysis of glucose utilization in Prochlorococcus and Synechococcus. (in preparation).
-Moreno-Cabezuelo JA, Issoglio F, Athayde D, Muñoz-Marín MC, López-Lozano A, Diez J, Archer M & García-Fernández JM. Structural features of the high affinity glucose transporter GlcH in Prochlorococcus sp. strain SS120. (in preparation)
Links
Contact details
Email: j.moreno-cabezuelo@uea.ac.uk